r8 women that party hard for any extended time are less likely to make it to past their 60s.

male or female, even if they've quit the damage done usually starts showing up by 50. If they don't and say started in their teens or earlier, we usually start seeing signs of internal damage by 30.

in part, why you see more male old homeless addicts than female... and of course, other factors come into play but the biological differences are no joke... in general, women are more prone to become addicts/alcoholics as they have a harder time discoveirng their limits, often when young they view blacking out or vomiting is the limit and so, this leading to greater possibility of overdosing. . . often in competition with the people around them. We got a lot of math here for bmi + activities, then life sciences so, male or female, the more petite you are, the greater chance for serious longterm damage. (though, fatties, you're as much at risk as well.)

they you've got lifestyle and fitness, given that women are less likely to workout to build/maintain muscle (while it's slowly changing, a lot of women are still afraid that anything other than cardio is going to give them man body) or do manual labor, so more prone to early muscle wasting (or obesity ) and more prone to fasting, cleanses and crash dieting leading to a variety of complications and possible disorders.

in average, fit, healthy people - females do the most damage in their 20s, males in their 30s... now they can be prodigy and start younger, but in general men need to quit partying within their late twenties to early thirties, women within in their early to mid twenties. ladies, that's your gift for physically maturing faster. Individual bio makeup may vary.

both ashkenazi and cuban have their own set of competing issues... more so from her generation and prior.

and those with starvation based eating disorders, has a long list of complications... even if recovered, they're more prone to sudden death (any number of reasons.. often related to previous stress damage) as well as early onset dementia and alzheimer's, and a host of neurological, motor control and autoimmune complications.

And just general mental health (she's been open about having severe anxiety; which can develop into heart related issues, but specifically stress.) and the celebrity lifestyle (high level stress.. stress itself is difficult for most people to manage and can cause massive physical damage to the body in varying ways)